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Applications for Microfat and Nanofat in Pain Management

The healing and regenerative potential of adipose tissue has proven invaluable to the field of peripheral nerve pain management. The application of microfat and nanofat has garnered attention as a promising avenue for addressing various peripheral nerve painful conditions.

These advanced techniques involve:

1. Harvesting small amounts of the patient’s own adipose tissue or Adipose Tissue Complex (ATC) and standardizing the injectability of the tissue. This is microfat and is a natural filler and volumizer.

2. Sizing the microfat down to Tissue Stromal Vascular Fraction (tSVF) or nanofat. Nanofat is regenerative in nature (not volumizing) and can be injected intradermally with a needle as small as 30g.

Tulip Medical continues to lead the industry by participating in research of biocellular regenerative therapies for pain. In the midst of an opioid crisis, microfat and nanofat offer a promising, natural, healthy, minimally-invasive choice for pain management.

The regenerative potential of microfat and nanofat offer benefits in alleviating pain and promoting tissue healing. In pain management, these fat grafts can be strategically injected into areas of chronic pain caused by peripheral nerve damage. Nerves love fat. Peripheral nerve hydrodissection with microfat and nanofat can relieve pain as well as correct the tissue degradation that causes the pain.

The regenerative capabilities of microfat and nanofat contribute to a holistic approach to pain management by addressing the underlying causes of pain rather than merely alleviating symptoms. As research progresses, these techniques will play an increasingly significant role in providing innovative, minimally invasive solutions for individuals seeking effective and long-lasting pain relief.

Pain Management Uses for Microfat and Nanofat

It’s important to note that while the potential applications of microfat and nanofat in pain management are promising,
further research and clinical studies are needed to establish the efficacy and safety of these approaches for various pain conditions.

Microfat and nanofat obtained with the Tulip Nano System can be used in a wide variety of office-based procedures:

  • Accelerate Healing Processes


  • Chronic
    Joint Pain

  • Soft Tissue Injuries

  • Neuropathic Pain

    Neuropathic Pain

  • Scar Revision

    Scar Tissue Management

  • Chronic Back Pain

    Chronic Back Pain

  • Use Autologous Tissues to Support Implants Surgery

    Facet Joint Pain

  • Peripheral Neuropathy (migraine, post-op pain)

    Headache and
    Migraine Management

  • Pain from
    Scarred Nerves

  • Temporomandibular
    Joint (TMJ) Disorders

Understanding the Difference Between Microfat and Nanofat

Microfat and nanofat are adipose fat tissues that maintain the regenerative properties of native fat. Microfat can often be delivered through blunt needles or cannulas that range from 18g to as small as 25g in diameter, depending on the fibrosity of the patient’s fat. Microfat adds volume and structure to the recipient site.

Nanofat’s primary benefit is regeneration. Nanofat consists of a regenerative matrix which is key to nerve and tissue repair and rejuvenation. True Nanofat™, obtained with the Tulip system, is validated to be injectable with needles as small as 30g.

Together, microfat and nanofat have the potential to provide relief to patients suffering from chronic pain without the need for invasive surgical procedures or addictive prescription narcotics.

Ziv M. Peled, MD

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Incorporating Regenerative Microfat and Nanofat into Your Pain Management Practice

Whether you use microfat and nanofat in a standalone procedure or in conjunction with other treatments, Tulip’s patented technology makes your experience with microfat and nanofat safe, easy, predictable and cost effective. As the leading company in fat transfer for over 30 years, Tulip has the expertise to help you incorporate the use of adipose regenerative therapies into your practice.

Everything You Need to Obtain Nanofat: The Tulip GOLD Kit

Tulip’s GOLD (Gentle Office-Based Lipoaspirate Delivery) kit provides everything you need to harvest and prepare microfat and nanofat for use in an office-based setting.

Using a closed syringe lipoaspiration system, our GOLD kits provide a less traumatic and more efficient approach to acquiring Adipose Tissue Complex (ATC) as a structural graft without surgery.

  • The protocol and the kit have been clinically validated for safety, ease of use, viability and consistent output leading to more predictable outcomes.
  • Tulip’s “Soft Harvest System” provides a safe and efficacious low-pressure acquisition of ATC.
  • From here, the harvested fat can be used as microfat (which is not sized down) or sized down into nanofat.
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Tulip GOLD Kits Provide These Advantages for Pain Management

  • Safe and easy to use closed adipose tissue harvesting and sizing
  • Validated process resulting in consistently high concentrations of regenerative ATC and nanofat that is validated to be injectable with needles as small as 30g
  • Increased patient safety by using their own tissue
  • Sets your practice apart by offering the regenerative therapies patients are asking for

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