The Difference Between tSVF & cSVF

Many doctors often ask "What's the difference between tSVF & cSVF?". While the two sound similar, there are several key differences.

tSVF → tissue SVF, the “lipoaspirant”, unprocessed total complex that includes the adipocytes themselves (the fat), blood vessels, etc.

• Includes all cellular and biological components of the tissue

• It has a bioactive matrix (an extracellular matrix aka a scaffolding)

• Requires no manipulation to be used but it can be manipulated to make particle size smaller and grafts more effective

• Can be found in ALL ATC deposits throughout the body and can be harvested & then used up by the microenvironment that has been degenerating/aging

• Once harvested and reintroduced to target site, the cells will reinforce the cells that are already in the site

• Individual cells are less effective than the complex itself → the tSVF is critical

cSVF → cellular SVF

• Requires digestion, incubation, and isolation process to create a “pellet”

• This pellet can then be given via IV or given back to the adipose tissue complex

• Does not have a matrix

• Commonly used in research settings and in “cell-enrichment” protocols

Have another question about tSVF, cSVF, or adipose regenerative therapies? Email our team at info@tulipmedical.com for answers.