The Difference Between tSVF & cSVF
Many doctors often ask "What's the difference between tSVF & cSVF?". While the two sound similar, there are several key differences.
tSVF → tissue SVF, the “lipoaspirant”, unprocessed total complex that includes the adipocytes themselves (the fat), blood vessels, etc.
Includes all cellular and biological components of the tissue
It has a bioactive matrix (an extracellular matrix aka a scaffolding)
Requires no manipulation to be used but it can be manipulated to make particle size smaller and grafts more effective
Can be found in ALL ATC deposits throughout the body and can be harvested & then used up by the microenvironment that has been degenerating/aging
Once harvested and reintroduced to target site, the cells will reinforce the cells that are already in the site
Individual cells are less effective than the complex itself → the tSVF is critical
cSVF → cellular SVF
Requires digestion, incubation, and isolation process to create a “pellet”
This pellet can then be given via IV or given back to the adipose tissue complex
Does not have a matrix
Commonly used in research settings and in “cell-enrichment” protocols
Have another question about tSVF, cSVF, or adipose regenerative therapies? Email our team at email@example.com for answers.